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Your medication questions,
answered in film.

30-second answers to the questions patients actually ask. Pick your medication.

Licensed cliniciansRefund if not prescribedCancel anytime503A U.S. pharmacies
You’ll see your price before you pay.
Tirzepatide acts on two gut-hormone receptors - GIP and GLP-1. Most GLP-1 medications act on one. FDA prescribing information, tirzepatide ↗
Hunger is not willpower, it is signalling. These medicines act on the same pathway your gut uses after a meal. FDA prescribing information, GLP-1 receptor agonists ↗
Adults taking the FDA-approved brand Zepbound® at 15 mg lost on average about 21% of body weight over 72 weeks. That trial studied the brand product, not compounded preparations. SURMOUNT-1, New England Journal of Medicine, 2022 ↗
By slowing how quickly the stomach empties, the feeling of being full arrives earlier in a meal and lasts longer. FDA prescribing information, mechanism of action ↗
A single weekly injection - not a daily negotiation with yourself. FDA prescribing information, dosing and administration ↗
These medicines were studied for chronic weight management together with diet and physical activity, not as a replacement for them. FDA-approved indication statement ↗
A prescription may be issued only after a practitioner establishes a valid patient relationship and determines the drug is medically appropriate. Federation of State Medical Boards, telemedicine policy ↗
Nausea is the most commonly reported side effect and is often dose-related. Tell your clinician about anything persistent or severe. FDA prescribing information, adverse reactions ↗
Compounded medications are not FDA-approved. FDA does not review them for safety, effectiveness, or quality before marketing. FDA guidance on human drug compounding ↗
Compounded drugs may be prepared for an identified patient only on receipt of a valid prescription; they are not FDA-approved and FDA does not review them for safety, effectiveness, or quality. FDA, Section 503A of the FD&C Act ↗
Takes about 10 minutes · a clinician can decline · full refund if not prescribed
About PinwellRx

How PinwellRx actually works

Cash pay only All 50 states 503A pharmacies Refund if not prescribed
Does PinwellRx accept insurance?

No. PinwellRx is cash pay only. No insurance is billed, so there is no claim, no deductible and no surprise statement later. You see the full price before you pay, and the clinician review and shipping are included.

Is PinwellRx available in my state?

PinwellRx works with licensed clinicians across all 50 states and ships nationwide where treatment is permitted. Specific medication availability can still vary by state and by pharmacy.

Who prescribes the medication?

An independent licensed clinician reviews your intake and decides whether treatment is medically appropriate. PinwellRx is a telehealth platform, not the prescriber, and not everyone qualifies.

Which pharmacy prepares it?

When prescribed, compounded medications are prepared and dispensed by appropriately licensed U.S. compounding pharmacies operating under Section 503A. PinwellRx does not manufacture or compound medication.

Who is behind PinwellRx?

PinwellRx was built by the same leadership behind URBN Dental, a multi-location practice that has served more than 50,000 patients over ten years.

What if a clinician does not prescribe?

You are refunded in full. There is no membership requirement, and you can cancel any time before your next fill.

Are compounded medications FDA-approved?

No. Compounded medications are not FDA-approved, and FDA does not review them for safety, effectiveness or quality before marketing. Brand products such as Zepbound and Wegovy are FDA-approved; compounded preparations are not the same thing.

See your price About 10 minutes · a clinician can decline · full refund if not prescribed
Oral tablets Swallowed once a day - no needles 2 medications
Oral Semaglutide For weight loss: the best-known GLP-1 molecule as a compounded daily tablet - it signals fullness sooner so you eat less, with no injection. Prepared by a licensed US pharmacy against your prescription; compounded medications are not FDA-approved. 01Semaglutide, carried past the stomach 02A daily tablet instead of a needle 03The GLP-1 receptor does the rest 7 films NAD+ Liposomal NAD+ wrapped in a protective lipid layer so more of it survives digestion - a needle-free daily alternative to the injection. Compounded medications are not FDA-approved. 01A lipid layer wraps the molecule 02More survives the trip through digestion 03A daily option with no needle Written explainer
Injectables Weekly or nightly shots you give yourself at home 5 medications
Tirzepatide A weight-loss medication. The compounded weekly injection works on two gut-hormone pathways - GIP and GLP-1 - slowing the stomach and quieting appetite, so fullness arrives sooner and you eat less. Prepared by a licensed US pharmacy against your prescription; compounded medications are not FDA-approved. 01Docks on two receptors, GIP and GLP-1 02The stomach slows, fullness arrives sooner 03Appetite quiets between meals 16 films Semaglutide A weight-loss medication. The best-known GLP-1 molecule, compounded as a weekly injection - it slows stomach emptying and signals fullness to the brain, so you feel satisfied sooner and eat less. B6 available in the blend to ease early nausea. Compounded medications are not FDA-approved. 01Slows how fast the stomach empties 02Docks on the GLP-1 fullness receptor 03The brain hears “enough” earlier 19 films Sermorelin A nightly peptide that asks your own pituitary to release growth hormone in its natural pulse - studied for deeper sleep and recovery rather than replacing the hormone from outside. 01Speaks to the pituitary at its base 02Your gland releases GH in natural pulses 03Deep-sleep repair runs on schedule 13 films NAD+ The coenzyme every cell spends on energy and repair, and which falls with age. Injectable NAD+ restores it directly, bypassing the gut entirely. 01Every cell spends NAD+ on energy 02Mitochondria burn it constantly 03Injection restores what age drains 14 films Metabolism Boost Injection (B12 + MIC) Methylcobalamin B12 with the three lipotropics your liver uses to process fat - methionine, inositol and choline - in one small weekly shot for energy and clarity. 01B12 builds blood cells and nerve sheaths 02MIC lipotropics help the liver process fat 03One weekly shot, steady energy 13 films
Microdosing A lower weekly dose, held steady 2 medications
Semaglutide Microdose A lower weekly dose of compounded semaglutide, held deliberately rather than titrated up on the standard schedule - for a gentler on-ramp. Whether a microdose suits you is a clinical judgement, not a preference you select. Compounded medications are not FDA-approved. 01A smaller weekly amount, held steady 02Fewer GLP-1 receptors engaged 03Same pathway, gentler signal Written explainer Tirzepatide Microdose A lower weekly dose of compounded tirzepatide, engaging both the GIP and GLP-1 pathways at a fraction of a standard schedule. How long a low dose fits you is decided at follow-up. Compounded medications are not FDA-approved. 01Both GIP and GLP-1 still activate 02A fraction of a standard dose 03Intensity differs, mechanism does not Written explainer
Sexual health Tablets and liposomal drops, matched by a clinician 6 medications
Tadalafil The long-window ED tablet, FDA-approved - up to 36 hours as needed, or a low daily dose so timing stops being a variable at all. Tadalafil can remain effective for up to 36 hours. That is how long it works, not how long it interacts with nitrates. The labeling says at least 48 hours should pass after the last tadalafil dose before nitrate treatment is even considered. If you need emergency care, tell the team that you take tadalafil and exactly when your last dose was. 01Same PDE5 mechanism, slower clock 02A window up to thirty-six hours 03Or one low dose, daily 2 films Sildenafil + Tadalafil Liposomal Both PDE5 inhibitors in one liposomal dose - sildenafil for a faster onset, tadalafil for a longer window. Works only alongside arousal. Compounded medications are not FDA-approved. 01Sildenafil moves fast 02Tadalafil runs long 03Both in one liposomal dose Written explainer Sildenafil + Tadalafil A compounded tablet pairing sildenafil’s faster onset with tadalafil’s long window - prescribed only when a clinician judges the combination right for you. Compounded medications are not FDA-approved. 01Fast onset from sildenafil 02Long tail from tadalafil 03One compounded tablet 2 films Tadalafil + Apomorphine Tadalafil keeps blood vessels relaxed locally; apomorphine acts centrally on dopamine receptors involved in arousal - two different points in the same chain. Compounded medications are not FDA-approved. The apomorphine labeling contraindicates taking it with any drug of the 5HT3 antagonist class. That class is the anti-nausea medicines ondansetron, granisetron, dolasetron and palonosetron, plus alosetron, which is used for the bowel. Profound low blood pressure and loss of consciousness have been reported when apomorphine was given with ondansetron. Ondansetron is one of the medicines most often prescribed for the nausea of a GLP-1, so if you take a GLP-1, or you are given anything for nausea by any clinician, say so before a preparation containing apomorphine is prescribed or taken. 01Tadalafil relaxes vessels locally 02Apomorphine acts centrally 03Two points in the same chain Written explainer Sildenafil + Apomorphine Sildenafil acts quickly and locally on blood flow; apomorphine acts centrally on the arousal pathway - intended for a faster response with central support behind it. Compounded medications are not FDA-approved. The apomorphine labeling contraindicates taking it with any drug of the 5HT3 antagonist class. That class is the anti-nausea medicines ondansetron, granisetron, dolasetron and palonosetron, plus alosetron, which is used for the bowel. Profound low blood pressure and loss of consciousness have been reported when apomorphine was given with ondansetron. Ondansetron is one of the medicines most often prescribed for the nausea of a GLP-1, so if you take a GLP-1, or you are given anything for nausea by any clinician, say so before a preparation containing apomorphine is prescribed or taken. 01Sildenafil acts fast on blood flow 02Apomorphine supports arousal signalling 03Speed locally, support centrally Written explainer Sildenafil + Tadalafil + Vardenafil + Apomorphine Four actives in one liposomal dose - three PDE5 inhibitors plus apomorphine acting centrally. Your clinician decides whether a multi-active formulation is appropriate for you. Compounded medications are not FDA-approved. The apomorphine labeling contraindicates taking it with any drug of the 5HT3 antagonist class. That class is the anti-nausea medicines ondansetron, granisetron, dolasetron and palonosetron, plus alosetron, which is used for the bowel. Profound low blood pressure and loss of consciousness have been reported when apomorphine was given with ondansetron. Ondansetron is one of the medicines most often prescribed for the nausea of a GLP-1, so if you take a GLP-1, or you are given anything for nausea by any clinician, say so before a preparation containing apomorphine is prescribed or taken. 01Three PDE5 inhibitors, different clocks 02Apomorphine adds central action 03Four actives, one liposomal dose Written explainer
Nasal No needle, no tablet - sprayed 1 medication
NAD+ Nasal Spray NAD+ as a measured nasal spray - the thin, richly vascular nasal lining carries it toward circulation with no needle, no cold chain, and nothing to schedule. 01A measured mist meets the nasal lining 02Thin, blood-rich tissue carries it in 03No needle, no cold chain 1 film
GLP-1 & peptide answers

Compounded semaglutide, tirzepatide, NAD+ and sermorelin questions, answered

Plain-English answers to what patients actually search: what compounded semaglutide and tirzepatide are, how GLP-1 medications work, whether they are FDA-approved, what NAD+ and sermorelin do, and what treatment costs. Every medical fact is attributed to FDA prescribing information or peer-reviewed research. PinwellRx speaks only for its own process, pricing, and refund policy - never for a treatment outcome.

Sources: FDA prescribing information, peer-reviewed clinical trials and NIH literature · Updated August 2026

What is compounded semaglutide?

Semaglutide prepared for one named patient by a licensed U.S. compounding pharmacy against a prescription. It is a GLP-1 receptor agonist. Compounded medications are not FDA-approved, and FDA does not review them for safety, effectiveness, or quality before marketing.

FDA prescribing information, semaglutide ↗

What is compounded tirzepatide?

Tirzepatide prepared for an individual patient by a licensed U.S. compounding pharmacy. Tirzepatide acts on two gut-hormone receptors, GIP and GLP-1, where most GLP-1 medications act on one. Compounded preparations are not FDA-approved.

FDA prescribing information, tirzepatide ↗

How do GLP-1 medications reduce appetite?

They engage GLP-1 receptors involved in satiety signalling and slow gastric emptying, so fullness arrives earlier in a meal and lasts longer. This is the mechanism described in FDA prescribing information, not a promised outcome.

FDA prescribing information, GLP-1 receptor agonists ↗

What is GLP-1 microdosing?

Taking a lower weekly dose than a standard titration schedule and holding it steady rather than escalating. The mechanism is unchanged; only the amount differs. It is not an FDA-approved dosing regimen and no published trial establishes its results.

FDA. Human drug compounding ↗

What is sermorelin?

A growth-hormone-releasing hormone analogue that prompts the pituitary to release growth hormone the body makes itself. It is not synthetic HGH and not an anabolic steroid. Compounded sermorelin is not FDA-approved.

FDA. Human drug compounding ↗

What does NAD+ do in the body?

NAD+ is a coenzyme every cell uses to carry electrons in energy metabolism, and it is consumed by repair-related enzymes. Levels decline with age. NAD+ is not an FDA-approved drug for any indication.

NIH. Dietary supplements ↗

Is compounded medication the same as the brand drug?

No. A compounded preparation is not FDA-approved, is not a generic, and is not established as equivalent to any FDA-approved product. Trial results for brand products describe those products only.

FDA. Compounding and the FDA ↗

Who decides whether treatment is appropriate?

An independent licensed clinician, after reviewing your intake. Completing an intake does not guarantee a prescription, and not everyone qualifies. PinwellRx is a telehealth platform; it does not prescribe, manufacture, or compound medication.

FDA. Section 503A of the FD&C Act ↗

How does PinwellRx pricing work?

Cash pay only, with no insurance billed and the price shown before payment. Compounded options start at $179 per 4 weeks. If a clinician does not prescribe, the payment is refunded in full.

PinwellRx refund policy ↗

Which states is treatment available in?

Availability varies by state and by pharmacy. A clinician licensed in your state must review your case, and some medications are not available everywhere.

PinwellRx state availability ↗

Definitions used on this page

Compounded medication - a preparation made by a licensed pharmacy for an individual patient; not FDA-approved. GLP-1 receptor agonist - a medicine that engages the GLP-1 receptor involved in satiety and gastric emptying. Titration - a planned dose increase over time, governed by your dispensed label. Microdose - a lower weekly dose held steady instead of escalated. 503A pharmacy - a state-licensed pharmacy compounding for individual prescriptions; this is a licensure category, not an FDA approval or endorsement.

Ready to see if this is right for you?

A licensed clinician reviews every intake. You’ll see your price before you pay, and nothing ships unless a clinician prescribes it.

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Takes about 10 minutes · a clinician can decline · full refund if not prescribed
Sources
Trial results and label statements belong to the cited FDA-approved products and publications - they are not claims about compounded medications. Compounded medications are not FDA-approved.
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Individual results vary and no outcome is guaranteed. Any figure quoted from a clinical trial describes the product studied in that trial at the doses studied, and is not a prediction for you.